Creatinine With eGFR
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Plasma separator tube or serum separator tube.
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.2 mL)
Refrigerated.
Specimens obtained through catheters used to infuse hyperalimentation fluid. Specimens collected with potassium oxalate/sodium fluoride or sodium citrate.
Patient age and sex are required for calculation.
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 3 months
Methodology
Quantitative Enzymatic Assay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Refer to Report
Calculated GFR - >= 60 mL/min / 1.73 square meters
Interpretive Data
The estimated glomerular filtration rate (eGFR) was calculated using the 2021 CKD-EPI eGFR creatinine equation, which does not include race as a factor. This equation is validated in individuals 18 years of age and older. Accurate estimation of GFR requires stable day-to-day creatinine. Creatinine-based eGFR is less accurate in patients with extremes of muscle mass, restriction of dietary protein, ingestion of creatine, extra-renal metabolism of creatinine, or treatment with medications that affect renal tubular creatinine secretion. The eGFR is normalized to a body surface area of 1.73 square meters.
GFR Categories in Chronic Kidney Disease (CKD) | ||
---|---|---|
GFR Category | GFR (mL/min/1.73 square meters) | Interpretation |
G1 | 90 or greater | Normal to high* |
G2 | 60-89 | Mild decrease* |
G3a | 45-59 | Mild to moderate decrease |
G3b | 30-44 | Moderate to severe decrease |
G4 | 15-29 | Severe decrease |
G5 | 14 or less | Kidney failure |
*In the absence of evidence of kidney damage, neither GFR category G1 nor G2 fulfill the criteria for CKD (Kidney Int Suppl 2013;3:1-150) |
FDA
Note
Hotline History
Hotline History
CPT Codes
82565
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0020025 | Creatinine, Serum or Plasma | 2160-0 |
3005479 | eGFR by CKD-EPI Creatinine 2021 | 98979-8 |
Aliases
- cGFR
- Calculated Glomerular Filtration Rate
- eGFR
- Estimated Glomerular Filtration Rate